Shelly Duttine asked 1 year ago

Bulldog Urinary Cystine Stones

Bulldog Urinary Cystine Stones  Hi, Dr. Kraemer

i have a 6.5 year iold intact male, bulldog mix (English, American, pocket pit) who was diagnosed with bladder stones (cystine) approximately 6 months ago.
Cystotomy July
cystotomy October
stones flushed back into bladder December

hes been on science diet u/d since October
we have been to 2 different vets and neither are very familiar with the cystine stones
One vet says to do PU surgery and stay on the science diet u/d
the other said the PU would help the stones to pass but he will be very prone to infections (we live in the country so lots of land and dirt) and says thiola drug and neuter and potassium citrate and science diet u/d
Are there any studies on the best treatment for the long term?

it sounds like PU surgery will enable the stones to pass but can cause many other issues.
the thiola is expensive and not sure if it will work
potassium citrate reviews do seem to be a method to keep the stones from forming.
i am just at a loss and exhausted so if there is any input or sites I can look at for advice it would be greatly appreciated!!
Thank you!


1 Answers
Dr. Kraemer Vet4Bulldog Staff answered 1 year ago

Dear Shelly

Bulldog cystine bladder stones are common to the breed especially younger male bulldogs yet constitute less than 2% in other breeds. The stone formation is likely due to your bulldog genetics and is thought to be a metabolic defect of your bulldog kidneys processing of cystine.

Strict dietary compliance is necessary to try and keep the urine PH neutral or higher (alkaline) and lower proteins. There are a few prescription veterinary diets available such us proplan HA and Hills Ud, increase water intake is also important (dilute urine).

Unfortunately, bulldog cystine stones are likely to recur despite removal and dietary changes, thus I concur with the vet who recommended the urethrostomy (scrotal is preferred). I have done many bulldog urethrostomies successfully, with little to no long-term complications (i.e. Cystitis).  You can add a urinary supplement that can help control infections and reduce the chances for drug resistance type due to biofilm (adherence to bladder wall) The permeant opening/stoma allows for the stones to drop thus prevents re-blockage.

Removal without a permeant new opening at the scrotal area despite adherence to the dietary recommendation is usually just a short-term relief. The chances are that your bulldog will present (usually as a very costly emergency) with a new urethral blockage or various degree of urinary distress in the coming months and years.

Dr. Kraemer Vet4Bulldog


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