MRSA and MRSP Infection in Bulldogs
and French Bulldogs

MRSA and MRSP Infection in Bulldogs and French Bulldogs (Multi Drug Resistance in Bulldogs)

MRSA and MRSP Infection in Bulldogs and French Bulldogs are becoming common finding in unresloved ear and skin infection. MRSA, stands for “Methicillin-Resistant Staphylococci Aureus” while  MRSP stands for “Methicillin-Resistant Staphylococci Pseudintermedius”. I am going to use the term “Multi Drug Resistant” interchangeably with “Methicillin Resistant” to simplify the terminology, please be aware of the difference between the two terms. In general, MRSA is an indigenous component of normal humans, NOT dogs. In contrast, MRSP is native to your English bulldog or French bulldog puppy skin, NOT to your family and yours skin.

MRSA and MRSP Infection in Bulldogs and French Bulldogs puppies also known as “multi drug resistance” infection

MRSA and MRSP Infection in Bulldogs and French Bulldogs puppies also known as “multi drug resistance” infection

In humans and animals skin, Staphylococci without clinical signs are classified as COLONIZED. Staphylococci that carry the methicillin-resistant gene are resistant to all beta-lactam antibiotic drugs. Methicillin-resistant infections in pets are an increasing problem in veterinary medicine and are driven by antibiotic pressure (i.e. overuse, indiscriminate, “blanket”, “defensive” etc).

Staphylococci bacteria are part of the normal mircoflora of your bulldog’s skin but may cause opportunistic infections in bulldog French and English puppies, adult bulldogs, and other dog breeds and cats who may have any underlying conditions that compromise their immune system and/or the skin barrier. The most common examples are allergies. The two most common allergies known to bulldogs are hypersensitivity to the environment (“Atopy”, “Atopic Dermatitis”) and hypersensitivity to Food (Food Allergy”). The other frequent underlying causes of compromised skin barrier are parasites such as fleas (Flea Allergy Dermatitis) and mites (demodex and scabies mites). Allergies and parasites are considered “primary cause” while most bacteria skin infection (“Pyoderma”) are usully secondary. Staphylococcus pseudintermedius is the most common bacteria found in bulldog puppies, adult bulldogs and other common dog breed pyodermas.

MRSA in dogs is rare and is usually the result of contact with a human carrier. Most bulldogs and other dog breeds exposed to MRSA do NOT develop clinical disease, and most will eventually eliminate the organism.  As in people, colonized animals usually show no adverse effects unless risk factors allow for development of clinical infection, those risk factors could be a recent surgical procurement, trauma, skin wounds, and immunosuppression. Unlike MRSA in people, which is often associated with increased morbidity and mortality, there does not appear to be a significant difference in patient outcome between dogs infected with MSSA (Methicllin SENSTIVE Stap Aureus) vs. MRSA (Methicillin RESISTENCE Stap Aureus), possibly because most infections are superficial (pyodermas and otitis) and not invasive.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs V4B  Maintenance:

MRSA and MRSP Infection in Bulldogs and French Bulldogs V4B Antiseptic Medicated Shampoo

MRSA and MRSP Infection in Bulldogs and French Bulldogs V4B Antiseptic Medicated Shampoo

I recommend treating bulldog puppies and adult bulldogs suffering from MRSP pyoderma with topical daily treatment in additional to selective oral antibiotics. Topical protocols are highly effective, some of the more effective topical solutions, sprays, shampoos and gels are:

1. Antiseptic shampoos: Frequent baths a medicated shampoo like Dr. Kraemer’s V4B Bulldog Anti Septic Shampoo w/PS, preferably 10 minutes of contact before rinsing.

2. Anti Septic Waterless Shampoos: On days you are unable to bathe your bulldog, I recommend you apply a waterless shampoo like Dr. Kraemer’s V4B Bulldog Anti Septic Gel w/PS, it only takes 30 seconds to do and is painless

3. High % Benzoyl Peroxide Shampoo :  Frequent baths with a medicated shampoo like Dr. KRaemer’s V4B Bulldog Degreasing Shampoo w/PS preferably 10 minutes of contact before rinsing. This shampoo is also an excellent follicular flushing agent, which helps remove debris and also has excellent keratolytic and degreasing effects. Again, on days you are unable to bathe your bulldog,  apply a waterless shampoo like Dr. Kraemer’s V4B Bulldog Anti Septic Gel w/PS.

4. Diluted Bleach: Daily soaks in diluted bleach 1:10 (1 part bleach to 10 parts water). You can sponge, bathe or soak,  but don’t rinse and leave your pet to air dry. You should prepare a fresh new dilute each time you bathe your pet.

5. Bactroban (mupirocin): is a good topical antibacterial ointment you can apply daily on your bulldog infected dermal areas.

6. Other Topical: like Dr. Kraeme’rs V4B Skin Fold wipes w/PS and V4B spray w/PS,  can be applied daily.

7. Oral Antibiotics: MRSP pyoderma systemic antibiotics are based on culture sensitivity results.

8. Other recommended supplements: Fish oil (omega 3 EFA) like Dr. Kraemer’s V4B Bulldog Fish Oil has anti-inflammatory properties and can improve various skin conditions and boost up the immune system. Other immune support supplements like Dr. Kraemer’s V4B Bulldog Immune Support can also help to enhance the immune system.

9. Manuka Oil: Essential oils from plants have long been used for medicinal purposes due to their antibacterial, antifungal, antiviral, antioxidant and insecticidal properties. Manuka oil has excellent antimicrobial activity and inhibits biofilm production. I don’t know enough about this oil use in bulldogs skin infection, how to apply, how often and if there are any drug interaction issues. I recommend you do some of your own research before using it.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs V4B Rule of Thumb:

Pyoderma caused by MRSP can present clinically like any other nonresistant staph strains and is NOT inherently a more dangerous infection. However, MRSP requires appropriate antimicrobial selection and should be based on culture and susceptibility testing. MRSP may be isolated from healthy individuals with no signs of disease; this is considered “colonization”, and is distinguished from “infection”, wherein the MRSP is causing signs of disease. Fortunately  Infections and disease attributed to MRSP are very rare in people, many of you bulldog owners and other pet owners have been exposed to it.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs V4B Tips & Warnings:

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #1: While the odds of you picking up MRSA or MRSP from your bulldog are very low, you should be vigilant and aware. Accordingly, the use of proper hygiene and infection control measures is always important, particularly around a pet with an active infection, these measures include:
-Frequent hand washing after contact with your infected bulldog.
-Avoiding contact with the infected site.
-Regular washing (in hot water with hot air drying, whenever possible) of your bulldog’s bed and other items that come into close and frequent contact with your pet.
-Keeping your bulldog puppy infected site covered.
-Reducing contact with your infected bulldog puppy nose, and, in general, reducing close contact with your bulldog (snuggling, nuzzling, hugging, and kissing) during the period of infection.
-Regular washing (in hot water with hot air drying, whenever possible) of your bulldog’s bed and other items that come into close and frequent contact with the pet.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs treated with stem cell therapy and cryobankin

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs treated with stem cell therapy and cryobankin

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #2: I have been treating chronic Atopic Itch Allergic Dermatitis with secondary MRSP with a new cutting edge regenerative medicine self healing treatment called Stem Cell Therapy This state of the art new therapeutic treatment is using your pet own anti inflammatory repair cell to enhance healing, repair the immune system, control itch and reduce inflammation.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #3: In contrast to a typical staphylocouccus pyodrema which often is treated symptomatically with antibiotic, MRSP antibacterial treatment choice should be based on a culture and sensitivity testing..

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #4 : Unlike MRSA in people, there is NOindication that MRSP is more virulent than methicillin-susceptible S. pseudintermedius (MSSP), and most reported infections have been treated successfully, though usually take longer to resolve.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #5: I treat MRSP for a much longer duration then I usually treat MSSP pyodrma.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #6: Clinical signs of methicillin-resistant infections are identical to methicillin-sensitive infections. Clinical suspicion of methicillin resistance includes lack of response to appropriate empiric therapy, worsening of signs while receiving therapy, and/or recurrent infections (particularly of the skin and ears).

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #7: Often methicillin-resistant staphylococcal infections in dogs and cats are complicated by secondary yeast overgrowth, and yeast infections, as well as primary or secondary seborrhea. Both of those secondary medical dermal conditions must be treated appropriately.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #8: Staphylococcus pseudintermedius is NOT a commensal organism in people and poses little zoonotic risk.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #9: All wounds should be kept covered to decrease the risk of environmental contamination. Hand hygiene and environmental disinfection at home are just as important as in the clinic.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #10: A methicillin-resistant infection should be suspected whenever there is poor response to empiric antibiotics, especially if a patient has a history of treatment with multiple prior antibiotics with limited improvement.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #11: when treating multi drug resistance staph pyoderma it is important to also treat the underlying or predisposing conditions (allergies, parasite, hypothyroid, etc).

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #12: Have your veterinarian reevaluate your bulldog during therapy to ensure appropriate response to treatment.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Tip #13: Disinfection of potentially contaminated surfaces is recommended

Warnings:

MRSA vs MRSP in bulldogs (Multi Drug Resistance ) Saved by SCBR

MRSA vs MRSP in bulldogs (Multi Drug Resistance ) Saved by SCBR

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #1: Potential risk factors for acquisition of MRSA colonization by pets include contact with children and contact with hospitalized patients, especially if pets are allowed to lick patients or be fed treats by patients.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #2: Although pets that are colonized or infected with MRSA most likely contracted the bacteria from people, pets may have the capability to be carriers of MRSA and subsequently pass it back to a human.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #3: Infected or colonized dogs should be exercised where they will not encounter other dogs. Infected or colonized cats should be kept indoors.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #4: While infection is active, owners should be discouraged from kissing their pet or allowing their pet to lick them.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #5: During treatment, owners should not allow the pet to sleep in their bed or with children.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #6: It is VERY important that you differentiate between MRSA and MRSP. Even though colonization of bulldogs with S. aureus is possible it is not very common since it is an indigenous component of normal humans, not dogs. Thus, if your bulldog becomes colonized, the pet may serve as a source for infection to people without ever manifesting clinical signs. Pet owners, rescue members and veterinary personnel who come in contact with S. Aureus colonized pets may then become MRSA carriers, which is why proper hygiene in those cases is so important.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #7: When suspecting MRSP I do not recommend empirical antibiotic treatment, a culture and sensitivity testing is required in order to assure treatment to which the MRSP is not resistant.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #8: If your bulldog was diagnosed with MRSA (Staph. aureus ) be aware of the potential for zoonotic transmission. In general the risk of clinical disease is probably low for immunocompetent people (i.e. health immune system) nevertheless everyone in contact with your dog should be alerted.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #9: Individuals who are immune compromised like ( HIV/AIDS, Chemotherapy, High Dose of immune suppressant drugs like Steroid / Prednisone and other chemotherapy drugs ) are more susceptible to contract MRSP from pets. Those immune incompetent and immune suppressed individuals should avoid contact with pets and high risk carrier like healthcare workers. In those cases it is prudent to contact a family physician and inform him/her of the situation. Precautions should be taken by these individuals to reduce the frequency of contacts with open wounds and pet feces.

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #10: Never treat methicillin-resistant infections bulldog with beta-lactam antibiotics (i.e. penicillins and cephalosporins), even if your veterinarian reports to you that the susceptibility test shows you can (consider it an error)

Dr. Kraemer’s MRSA and MRSP Infection in Bulldogs and French Bulldogs Warning #11: One of the most common reasons for partial response to antibiotic treatment of Pyoderma is too short a duration In addition, insufficient duration or non-compliant owners can lead to bacteria multi-drug resistance.

*This guide was compiled courtesy of Dr. Kraemer, a “must read” manual for any current or future bully owner.

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